TNF-alpha

Article No AFC-4536-2
Product Type Antibodies Primary
Research Area Cell Signaling
Application FC, IHC-Fr, ICC, ELISA, FA
Size 0.1 mg

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone MAb11
Clone Type monoclonal
Concentration 1 mg/ml
Conjugation Unconjugated
Description Mouse Monoclonal to TNF-alpha
Supplier BioSite Flow
Immunogen Recombinant human TNF-alpha
Isotype IgG1
Keywords Cytokine Signaling (Human)
Notes TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.
Purification Purified by protein-A affinity chromatography
Purity > 95% (by SDS-PAGE)
Species Reactivity human, monkey, pig/porcine
Storage Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Technical Specifications The mouse monoclonal antibody MAb11 recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

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Species reactivity:

human, monkey, pig/porcine human monkey