Article No
AFC-7Z7ZIF-0.1
Anti-Hu CD361 Purified
Anti-Hu CD361 Purified
Antibodies Primary
Specifications
| Application | FC, IP |
| Article No | AFC-7Z7ZIF-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | MEM-216 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-Hu CD361 Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 2124 |
| Format | Purified |
| Immunogen | Raji cells |
| Isotype | IgG1 k |
| Keywords | CD and Related Antigens (Human) |
| Notes | CD361, also known as EVI2B (ecotropic viral integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow. |
| Alias Names | EVI2B, EVDB |
| Previous Article No | AFC-4498-2, AFC-7Z7ZIF-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 1-4 µg/ml, Positive control, Positive control: Raji, Daudi, HL-60 cells, peripheral blood lymphcocytes (strongly positive on CD19+ cells), negative control: Jurkat, U-937 cells. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Immunology |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The mouse monoclonal antibody MEM-216 recognizes an extracellular epitope of CD361 / EVI2B, almost uncharacterized type I transmembrane protein with broad leukocyte expression, mostly in myeloid and B cells. |
| UniProt Number | P34910 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
