Article No
AFC-EI6JGY-0.1
Specifications
| Application | WB |
| Article No | AFC-EI6JGY-0.1 |
| Biosite Brand | Biosite Flow |
| Country Availability | all |
| Clone | BRG-01 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Anti-BRG1 Purified |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 6597 |
| Format | Purified |
| Immunogen | Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1. |
| Isotype | IgG2a |
| Keywords | Transcription Regulation & Nuclear Proteins, Transcription Regulation & Nuclear Proteins (Human) |
| Notes | Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression. |
| Alias Names | CSS4, SMARCA4, SNF2, SWI2, MRD16, RTPS2, BAF190, SNF2L4, SNF2LB |
| Previous Article No | AFC-4429-2, AFC-EI6JGY-0.1 |
| Product Type | Antibodies Primary |
| Protocol | Western blotting: Recommended dilution: 10 μg/ml; positive control: HEK293 cells. |
| Purification | Purified by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Research area | Cell Proliferation |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. |
| Substrate / Buffer | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Technical Specifications | The antibody BRG-01 recognizes an epitope within C-terminal part of human Brg1, a 205 kDa catalytic subunit of SWI2/SNF2-family chromatin-remodeling complexes. |
| UniProt Number | P51532 |
| Product Page Updated | 2024-01-03T12:18:20.318Z |
