Article No AFC-4325-2
Product Type Antibodies Primary
Research Area Cell Signaling
Application WB
Size 0.1 mg


Country Availability all
BioSite Brand BioSite Flow
Clone SO1
Clone Type monoclonal
Concentration 1 mg/ml
Conjugation Unconjugated
Description Mouse Monoclonal to SOCS3 / Suppressor of cytokine signaling
Supplier BioSite Flow
Immunogen Full-length SOCS3 protein.
Isotype IgG2b
Keywords Cytokine Signaling (Human)
Notes SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.
Purification Purified by protein-A affinity chromatography
Purity > 95% (by SDS-PAGE)
Species Reactivity human
Storage Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Technical Specifications The antibody SO1 reacts with SOCS3, an intracellular cytokine signaling inhibitor.
Product Page Updated 2018-07-27T09:12:01.609Z

Shipping info

The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot