CD38
Specifications
| Country Availability | all |
| BioSite Brand | BioSite Flow |
| Clone | HIT2 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Mouse Monoclonal to CD38 |
| Supplier | BioSite Flow |
| Immunogen | Human thymocytes in foetus |
| Isotype | IgG1 |
| Keywords | CD and Related Antigens (Human) |
| Notes | CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration. |
| Purification | Purified by protein-A affinity chromatography |
| Purity | > 95% (by SDS-PAGE) |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Substrate / Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Technical Specifications | The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.<br><b>HLDA III; WS Code T 155</b> |
| Product Page Updated | 2018-07-27T09:12:01.609Z |
Shipping info
The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.
Species reactivity:
human
Suggested protocols:
Western Blot