Article No
AFC-4288-2
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Suggested protocols
Specifications
| Application | FC, WB, IHC, IHC |
| Article No | AFC-4288-2 |
| BioSite Brand | BioSite Flow |
| Clone | HIT2 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | Mouse Monoclonal to CD38 |
| Supplier | BioSite Flow |
| Immunogen | Human thymocytes in foetus |
| Isotype | IgG1 |
| Keywords | CD and Related Antigens (Human) |
| Notes | CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration. |
| Product Type | Antibodies Primary |
| Purification | Purified by protein-A affinity chromatography |
| Purity | > 95% (by SDS-PAGE) |
| Research Area | Immunology |
| Size | 0.1 mg |
| Species Reactivity | human |
| Storage | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Substrate / Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Technical Specifications | The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.<br><b>HLDA III; WS Code T 155</b> |
| Product Page Updated | 2019-05-20T06:41:23.567Z |
Shipping info
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