Antibodies Primary

CD38

NEW
Mouse Monoclonal to CD38

Article No

AFC-4288-2

Application

FC, WB, IHC, IHC

Species Reactivity

human

Size

0.1 mg

Clone

HIT2

Specifications

Application FC, WB, IHC, IHC
Article No AFC-4288-2
BioSite Brand BioSite Flow
Clone HIT2
Clone Type monoclonal
Concentration 1 mg/ml
Conjugation Unconjugated
Description Mouse Monoclonal to CD38
Supplier BioSite Flow
Immunogen Human thymocytes in foetus
Isotype IgG1
Keywords CD and Related Antigens (Human)
Notes CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.
Product Type Antibodies Primary
Purification Purified by protein-A affinity chromatography
Purity > 95% (by SDS-PAGE)
Research Area Immunology
Size 0.1 mg
Species Reactivity human
Storage Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Technical Specifications The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.<br><b>HLDA III; WS Code T 155</b>
Product Page Updated 2019-05-20T06:41:23.567Z

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