TRIM

Article No AFC-4268-2
Product Type Antibodies Primary
Research Area Immunology
Application FC, IP, WB
Size 0.1 mg

Specifications

Country Availability all
BioSite Brand BioSite Flow
Clone TRIM-04
Clone Type monoclonal
Concentration 1 mg/ml
Conjugation Unconjugated
Description Mouse Monoclonal to TRIM / TRAT1
Supplier BioSite Flow
Immunogen Recombinant intracellular domain (aa 29-186) of human TRIM.
Isotype IgG2a
Keywords Adaptor Proteins (Human), Adaptor Proteins
Notes TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
Purification Purified by protein-A affinity chromatography
Purity > 95% (by SDS-PAGE)
Species Reactivity human
Storage Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Technical Specifications The antibody TRIM-04 reacts with T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
Product Page Updated 2018-07-27T09:12:01.609Z

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Species reactivity:

human human