Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.
Purified by protein-A affinity chromatography
> 95% (by SDS-PAGE)
human, cow/bovine, pig/porcine
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas; it is also present in tumors of B cell origin such as insulinoma._x000D_
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