CD279 / PD-1

Article No AFC-27C56B
Product Type Antibodies Primary
Application FC, IHC, FA
Size 0.1 mg


Country Availability all
BioSite Brand BioSite Flow
Clone EH12.2H7
Clone Type monoclonal
Conjugation Unconjugated
Description Mouse Monoclonal to CD279 / PD-1
Supplier BioSite Flow
Isotype IgG1
Keywords CD and Related Antigens (Human)
Notes CD279 / PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its receptors CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis.
Purification Purified by protein-A affinity chromatography
Purity > 95% (by SDS-PAGE)
Species Reactivity human, monkey
Storage Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Substrate / Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Technical Specifications The mouse monoclonal antibody EH12.2H7 recognizes CD279 / PD-1 (programmed cell death 1), a 55 kDa type I transmembrane protein expressed above all during T cell development, on activated T cells, activated B cells, and activated monocytes.
Product Page Updated 2019-05-16T11:08:57.063Z

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Species reactivity:

human, monkey human monkey

Suggested protocols: