Antibodies Primary

AQP2 (Ser264)

NEW
AQP2 (Ser264) Antibody

Article No

ACC-252522

Application

ELISA, WB

Species Reactivity

dog/canine
cow/bovine
chicken
human
mouse

Size

0.1 ml

Suggested protocols

Specifications

Application ELISA, WB
Article No ACC-252522
Country Availability DK, EE, FI, IS, LT, LV, NO, SE
Clone Type polyclonal
Description AQP2 (Ser264) Antibody
Supplier Abbiotec LLC
Isotype Ig
Notes Aquaporin-2 (AQP-2) forms a water specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. It is expressed in the renal collecting tubules. Defects in AQP-2 are a cause of autosomal recessive nephrogenic diabetes insipidus (ANDI), also known as diabetes insipidus nephrogenic type 2. It is characterized by excessive water drinking (polydypsia) and urine excretion (polyuria). AQP-2 belongs to the MIP/aquaporin (TC1.A.8) family. Serine-264 has been identified as a phosphorylation site on AQP2 and shown to be regulated by vasopressin thus implicating this site as important in AQP2 trafficking and subcellular distribution.
Alias Names Aquaporin-2; AQP2; Aquaporin protein-2; AQP-2; Aquaporin-CD; AQP-CD; Water channel protein for renal collecting duct; ADH water channel; Collecting duct water channel protein; WCH-CD
Product Type Antibodies Primary
Protocol E: 1:1,000; WB: 1:1,000
Research Area Metabolism
Size 0.1 ml
Species Reactivity dog/canine, cow/bovine, chicken, human, mouse
Storage Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Substrate / Buffer Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Technical Specifications Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Product Page Updated 2018-05-09T13:55:12.357Z

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