Article No
AC-0018
Specifications
| Application | IHC |
| Article No | AC-0018 |
| Country Availability | SE, FI, DK, NO, IS, FO, GL |
| Clone | EP14 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Cytokeratin 15 |
| Supplier | Cell Marque (Epitomics) |
| Format | Concentrate |
| Notes | Cytokeratin 15 (CK15) is involved in the development of stratified epithelia from one-layered polar epithelia and continues to be expressed in several adult epithelial tissues. It labels the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Although CK15 in normal hair follicles was virtually absent from hair bulbs, it was expressed by a subset of keratinocytes in the outer root sheath. In human conjunctival epithelium, strong expression of CK15 was observed in basal cells, whereas Cytokeratin 19 was expressed in both basal and suprabasal layers. CK15 may be used to differentiate primary from metastatic skin cancer. It may be a useful stem cell marker for hair follicle and breast epithelium. |
| Product Type | Antibodies Primary |
| Protocol | IHC: 1:100-200 |
| Research area | Clinical Diagnostic |
| Size | 1 mL |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Store at 2-8 °C. Don’t use after expiration date provided on the vial. The users must validate any storage conditions other than those specified. |
| Substrate / Buffer | Antibody to CK15 is affinity purified and diluted in 10 mM Phosphate buffered saline (PBS), pH 7.2 containing 1% bovine serum albumin (BSA) and 0.09% sodium azide (NaN3). |
| Technical Specifications | This antibody gives cytoplasmic staining in positive cells. The recommended positive controls are skin for normal tissue and skin cancer for abnormal tissue. Interpretation of the staining result should be combined with an established clinical product or procedure. |
| Product Page Updated | 2023-10-02T09:48:37.458Z |
