Article No
AC-0003
Specifications
| Application | IHC |
| Article No | AC-0003 |
| Country Availability | SE, FI, DK, NO, IS, FO, GL |
| Clone | EP6 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | E-Cadherin |
| Supplier | Cell Marque (Epitomics) |
| Format | Concentrate |
| Notes | E-Cadherin is a transmembrane glycoprotein, plays an important role in epithelial cell adhesion. A decreased expression of E-Cadherin is associated with metastatic potential and poor prognosis in breast cancer and esophagus cancer. In combination with p120 Catenin or Cytokeratin, it is useful for the differentiation between ductal (E-Cadherin positive) and lobular (E-Cadherin negative) breast carcinomas. It may also help in diagnosis of mesothelioma. |
| Product Type | Antibodies Primary |
| Protocol | IHC: 1:100-200 |
| Research area | Clinical Diagnostic |
| Size | 1 mL |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Store at 2-8 °C. Don’t use after expiration date provided on the vial. The users must validate any storage conditions other than those specified. |
| Substrate / Buffer | Antibody to E-Cadherin is affinity purified and diluted in 10 mM Phosphate buffered saline (PBS), pH 7.2 containing 1% bovine serum albumin (BSA) and 0.09% sodium azide (NaN3). |
| Technical Specifications | This antibody gives membrane staining in positive cells. The recommended positive controls are Colon for normal tissue and Colon cancer for abnormal tissue. Interpretation of the staining result should be combined with an established clinical product or procedure. |
| Product Page Updated | 2023-10-02T09:48:37.458Z |
