Article No
A64430-100
Cytotoxin 4 Polyclonal Antibody
Cytotoxin 4 Polyclonal Antibody
Antibodies Primary
Specifications
| Application | ELISA |
| Article No | A64430-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Cytotoxin 4 Polyclonal Antibody |
| Supplier | Epigentek |
| Format | Protein G Purified |
| Immunogen | Recombinant Naja atra Cytotoxin 4 protein (22-81AA) |
| Isotype | IgG |
| Keywords | Immunology & Inflammation |
| Notes | Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation. |
| Alias Names | Cytotoxin 4, CTX-4M, CTX4 |
| Product Type | Antibodies Primary |
| Purity | Protein G purified |
| Research area | Immunology |
| Size | 100 µl |
| Source / Host | rabbit |
| Species Reactivity | other vertebrates |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
| Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| UniProt Number | P01443 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
