Article No
A60391-100
PPP2R4 Polyclonal Antibody, Biotin Conjugated
PPP2R4 Polyclonal Antibody, Biotin Conjugated
Antibodies Primary
Specifications
| Application | ELISA |
| Article No | A60391-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone Type | polyclonal |
| Conjugation | Biotin |
| Description | PPP2R4 Polyclonal Antibody, Biotin Conjugated |
| Supplier | Epigentek |
| Immunogen | Recombinant Human Serine/threonine-protein phosphatase 2A activator protein (1-250AA) |
| Isotype | IgG |
| Keywords | Signal Transduction |
| Notes | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A. |
| Alias Names | Serine/threonine-protein phosphatase 2A activator (EC:5.2.1.8), PPP2R4, PTPA, PP2A, subunit B', PR53 isoform, Phosphotyrosyl phosphatase activator, PTPA, Serine/threonine-protein phosphatase 2A regulatory subunit 4, Serine/threonine-protein phosphatase 2A regulatory subunit B' |
| Product Type | Antibodies Primary |
| Purity | Protein G purified |
| Research area | Cell Signaling |
| Size | 100 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
| Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| UniProt Number | Q15257 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
