Article No
A58219-050
Application | ELISA |
Article No | A58219-050 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
Clone Type | polyclonal |
Conjugation | Biotin |
Description | ATXN7L3 Polyclonal Antibody, Biotin Conjugated |
Supplier | Epigentek |
Immunogen | Recombinant Human Ataxin-7-like protein 3 protein (51-347AA) |
Isotype | IgG |
Keywords | Other Histone Modification |
Notes | Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. _x000D_ |
Alias Names | Ataxin-7-like protein 3UniRule annotation, ATXN7L3, SAGA-associated factor 11 homolog |
Product Type | Antibodies Primary |
Purity | Protein G purified |
Research Area | Epigenetics |
Size | 50 µl |
Source / Host | rabbit |
Species Reactivity | human |
Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
UniProt Number | Q14CW9 |
Product Page Updated | 2024-02-13T10:42:34.821Z |