Article No
A54974-020
Disintegrin EC3B Polyclonal Antibody
Disintegrin EC3B Polyclonal Antibody
Antibodies Primary
Specifications
| Application | ELISA |
| Article No | A54974-020 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Disintegrin EC3B Polyclonal Antibody |
| Supplier | Epigentek |
| Immunogen | Recombinant Echis carinatus Disintegrin EC3B protein (1-67AA) |
| Isotype | IgG |
| Notes | Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins. The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit. The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B. |
| Alias Names | Disintegrin EC3B |
| Product Type | Antibodies Primary |
| Purity | Protein G purified |
| Research area | Epigenetics |
| Size | 20 µl |
| Source / Host | rabbit |
| Species Reactivity | other vertebrates |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
| Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| UniProt Number | P81631 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
