Article No
A50432-050
Application | ELISA, IHC, IF |
Article No | A50432-050 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | PTGDS Polyclonal Antibody |
Supplier | Epigentek |
Immunogen | Recombinant Human Prostaglandin-H2 D-isomerase protein (23-190AA) |
Isotype | IgG |
Keywords | Cell Metabolism, Cell Trafficking |
Notes | Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. |
Alias Names | Beta-trace protein, Cerebrin-28, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2, PDS, PTGDS |
Product Type | Antibodies Primary |
Purity | Protein G purified |
Research area | Metabolism |
Size | 50 µl |
Source / Host | rabbit |
Species Reactivity | human |
Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
UniProt Number | P41222 |
Product Page Updated | 2024-02-13T10:42:34.821Z |