Article No
A50103-050
CBX5 Polyclonal Antibody, FITC Conjugated
CBX5 Polyclonal Antibody, FITC Conjugated
Antibodies Primary
Specifications
| Application | ELISA |
| Article No | A50103-050 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone Type | polyclonal |
| Conjugation | FITC |
| Description | CBX5 Polyclonal Antibody, FITC Conjugated |
| Supplier | Epigentek |
| Immunogen | Recombinant Human Chromobox protein homolog 5 protein (1-191AA) |
| Isotype | IgG |
| Keywords | Chromatin Remodeling |
| Notes | Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. |
| Alias Names | Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, CBX5, HP1A |
| Product Type | Antibodies Primary |
| Purity | Protein G purified |
| Research area | Epigenetics |
| Size | 50 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. |
| Substrate / Buffer | 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4 |
| UniProt Number | P45973 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
