Article No
A303-866A-T
ACL
Rabbit anti-ACL Antibody, Affinity Purified
Antibodies Primary
Specifications
| Accession Number | NP_942127.1 |
| Application | IP, WB |
| Article No | A303-866A-T |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | 1000 ug/ml |
| Conjugation | Unconjugated |
| Description | Rabbit anti-ACL Antibody, Affinity Purified |
| Recommended Dilution | IP 2 - 10 µg/mg, WB 1:2000 - 1:10000 |
| Supplier | Bethyl Laboratories |
| Entrez Gene ID | 47 |
| Format | Whole IgG |
| Gene Symbol | ACLY |
| Immunogen | Between 350 and 400 |
| Isotype | IgG |
| Notes | Rabbit anti-ACL Antibody, Affinity Purified |
| Alias Names | ACL, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, ATPCL, citrate cleavage enzyme, CLATP |
| Predicted Species Reactivity | cow/bovine, rat, sheep/ovine |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Cell Signaling |
| Size | 10 µg |
| Source / Host | rabbit |
| Species Reactivity | human, mouse |
| Stability | 1 year from date of receipt |
| Storage | 4°C |
| Substrate / Buffer | Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide |
| Technical Specifications | ATP citrate lyase (ACL) is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. ACL is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ACL may be involved in the biosynthesis of acetylcholine [taken from NCBI Entrez Gene (Gene ID: 47)]. |
| UniProt Number | P53396 |
| Product Page Updated | 2024-04-10T10:28:22.747Z |
| Volume | 10 µl |
