Article No
A-1018-010
5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody [HMC/4D9]
5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody [HMC/4D9]
Antibodies Primary
Specifications
| Application | IF, IHC, ELISA, WB, Epigenetics |
| Article No | A-1018-010 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, GL |
| Clone | HMC/4D9 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | 5-Hydroxymethylcytosine (5-hmC) Monoclonal Antibody [HMC/4D9] |
| Supplier | Epigentek |
| Format | Affinity Purified |
| Isotype | IgG1 |
| Keywords | DNA Methylation |
| Notes | 5-hydroxymethylcytosine (5-hmC), as a sixth DNA base with functions in transcription regulation, has been detected to be abundant in human and mouse brain and embryonic stem (ES) cells. In mammals, it can be generated by oxidation of 5-methylcytosine (5-mC), a reaction mediated by the ten-eleven translocation (TET) family of 5-mC hydroxylases. 5-hmC was demonstrated to play an important and different role than 5-mC in the regulation of DNA methylation, chromatin remodeling, and gene expression |
| Alias Names | 5-hydroxymethylcytidine, anti-5-hydroxymethylcytidine, anti-5-hydroxymethylcytosine, anti-5hmC, anti-5-hmC, anti-5-hmeC, anti-5hmeC, 5hmC, 5hmeC, 5-hmeC |
| Product Type | Antibodies Primary |
| Purity | Affinity Purified |
| Research area | Epigenetics |
| Size | 10 µg |
| Source / Host | mouse |
| Species Reactivity | multi species |
| Storage | Shipped at 4°C. Aliquot store at -20°C . Avoid repeated freeze / thaw cycles. |
| Substrate / Buffer | 10 mM phosphate buffer, 150 mM NaCl, pH 7.4 |
| Product Page Updated | 2024-02-13T10:42:34.821Z |
