5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]

Article No A-1014-050
Product Type Antibodies Primary
Research Area Epigenetics
Application WB, IHC, IF, ELISA, IP
Format Affinity Purified
Size 50 µg

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Country Availability DK, EE, FI, FK, GL, IS, LT, LV, NO, SE
Clone 33D3
Clone Type monoclonal
Conjugation Unconjugated
Data Sheet Link http://www.epigentek.com/docs/A-1014.pdf
Description 5-Methylcytosine (5-mC) Monoclonal Antibody [33D3]
Supplier Epigentek
Isotype IgG1
Keywords DNA Methylation
Notes 5-methylcytosine (5-mC) is formed when DNA methyltransferase (DNMT) catalyzes the addition of a methyl group onto the 5-carbon of the cytosine ring, an epigenetic process known as DNA methylation. 5-mC is considered the "fifth" DNA base and this 5-methylcytosine mouse monoclonal antibody is ideal for discriminating between the unmodified cytosine base (C) and the methylated cytosine base (5-mC) for DNA methylation studies. DNA methylation, the major epigenetic modification of eukaryotic genomes, plays an essential role in mammalian development. DNA methylation of promoter regions leads to inactivation of gene function. Also, DNA methylation status varies according to tissue type, and region-specific DNA hypermethylation and global DNA hypomethylation have been demonstrated to play an important role in tumorigenesis.
Alias Names 5-methylcytidine, anti-5-methylcytidine, anti-5-methylcytosine, anti-5mC, anti-5-mC, anti-5meC, anti-5-meC, 5mC, 5meC, 5-meC, 5'-methyl-2'-deoxycytidine, 5MedCyd
Source / Host mouse
Species Reactivity species independent
Product Page Updated 2019-01-02T14:39:16.798Z

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mouse mouse

Species reactivity:

species independent

Product insert:

Product data sheet