Article No
42-1329-100
Application | ELISA, IP, WB |
Article No | 42-1329-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 1G10.H8 |
Clone Type | monoclonal |
Conjugation | ATTO 594 |
Description | Anti-HSP40, YDJ1 Monoclonal Antibody (Clone : 1G10.H8) - ATTO 594 |
Supplier | Abeomics |
Entrez Gene ID | 855661 |
Gene Symbol | YDJ1 |
Immunogen | Full length protein yeast HSP40 (YDJ1) |
Isotype | IgG1 k |
Notes | Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of HSP40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not. Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1. |
Alias Names | YDJ1||MAS5||YNL064C||N2418||YNL2418C |
Product Type | Antibodies Primary |
Protocol | WB (1:2000); optimal dilutions for assays should be determined by the user. |
Purification | Protein G Purified |
Shipping Information | Blue Ice |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | yeast |
Storage | 4°C |
Substrate / Buffer | 50% glycerol, 0.09% sodium azide |
UniProt Number | P25491 |
Product Page Updated | 2024-02-06T07:35:53.072Z |