Article No
42-1329-100
HSP40, YDJ1
Anti-HSP40, YDJ1 Monoclonal Antibody (Clone : 1G10.H8) - ATTO 594
Antibodies Primary
Specifications
| Application | ELISA, IP, WB |
| Article No | 42-1329-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 1G10.H8 |
| Clone Type | monoclonal |
| Conjugation | ATTO 594 |
| Description | Anti-HSP40, YDJ1 Monoclonal Antibody (Clone : 1G10.H8) - ATTO 594 |
| Supplier | Abeomics |
| Entrez Gene ID | 855661 |
| Gene Symbol | YDJ1 |
| Immunogen | Full length protein yeast HSP40 (YDJ1) |
| Isotype | IgG1 k |
| Notes | Human HSP40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain. There are two main types of HSP40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding, type II does not. Members of the HSP40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. HSP40 stimulates the ATPase activity of HSP70 which in turn causes conformational changes of the unfolded proteins. The HSP40-HSP70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1. |
| Alias Names | YDJ1||MAS5||YNL064C||N2418||YNL2418C |
| Product Type | Antibodies Primary |
| Protocol | WB (1:2000); optimal dilutions for assays should be determined by the user. |
| Purification | Protein G Purified |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | yeast |
| Storage | 4°C |
| Substrate / Buffer | 50% glycerol, 0.09% sodium azide |
| UniProt Number | P25491 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
