Article No
36-3823-20
CD4
Anti-CD4, Mouse (T-Cell Marker) Monoclonal Antibody(Clone: GK1.5)
Antibodies Primary
Specifications
| Application | ELISA, FC, IF |
| Article No | 36-3823-20 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | GK1.5 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD4, Mouse (T-Cell Marker) Monoclonal Antibody(Clone: GK1.5) |
| Supplier | Abeomics |
| Entrez Gene ID | 12504 |
| Gene Symbol | Cd4 |
| Immunogen | Mouse CTL clone V4 |
| Isotype | IgG2b k |
| Notes | CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines. |
| Alias Names | CD4 (L3T4); CD4; CD4+ Lymphocyte deficiency, included; Leu3; Ly-4; Lymphocyte antigen CD4; p55; T cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4 |
| Product Type | Antibodies Primary |
| Protocol | ELISA (For coating, order Ab without BSA & Azide); Neutralization Studies (Order Ab without BSA & Azide); Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml) |
| Shipping Information | Blue Ice |
| Size | 20 µg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P06332 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
