Article No
36-3666-100
CD81 / TAPA-1
Anti-CD81 / TAPA-1 Monoclonal Antibody(Clone: 1.3.3.22)
Antibodies Primary
Specifications
| Application | FA, FC, IF, IHC, WB |
| Article No | 36-3666-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 1.3.3.22 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD81 / TAPA-1 Monoclonal Antibody(Clone: 1.3.3.22) |
| Supplier | Abeomics |
| Entrez Gene ID | 975 |
| Gene Symbol | CD81 |
| Immunogen | B-Cell line derived from a Burkitt lymphoma |
| Isotype | IgG1 k |
| Notes | Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. |
| Alias Names | CD81; Target of the antiproliferative antibody 1 (TAPA-1); Tetraspanin-28; Tspan-28 |
| Product Type | Antibodies Primary |
| Protocol | Functional Studies (Order Ab without Azide);Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml for 2 hours at RT);Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P60033 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
