Article No
36-3636-0.5
CD63 (Late Endosomes Marker)
Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody(Clone: MX-49.129.5)-CF488
Antibodies Primary
Specifications
| Application | FC, IF |
| Article No | 36-3636-0.5 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MX-49.129.5 |
| Clone Type | monoclonal |
| Conjugation | CF488 |
| Description | Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody(Clone: MX-49.129.5)-CF488 |
| Supplier | Abeomics |
| Entrez Gene ID | 967 |
| Gene Symbol | CD63 |
| Immunogen | Full length CD63 of human origin |
| Isotype | IgG1 k |
| Notes | This MAb recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression. |
| Alias Names | gp55; granulophysin; Lysosomal-associated membrane protein 3 (LAMP-3); Mast cell antigen AD1; melanoma 1 antigen; Melanoma-associated antigen MLA1; Melanoma-associated antigen ME491; MLA1; NGA; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin-30; TSPAN30 |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood);Immunofluorescence (1:50-1:100) |
| Shipping Information | Blue Ice |
| Size | 0.5 ml at µg/ml |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | 4°C |
| Substrate / Buffer | Antibody Purified from Bioreactor Concentrate by Protein A/G and conjµgated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format. |
| UniProt Number | P08962 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
