Article No
36-3543-20
CD20 / MS4A1 (B-Cell Marker)
Anti-CD20 / MS4A1 (B-Cell Marker) Monoclonal Antibody(Clone: L26)
Antibodies Primary
Specifications
| Application | FC, IF, IHC, WB |
| Article No | 36-3543-20 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | L26 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD20 / MS4A1 (B-Cell Marker) Monoclonal Antibody(Clone: L26) |
| Supplier | Abeomics |
| Entrez Gene ID | 931 |
| Gene Symbol | MS4A1 |
| Immunogen | Human tonsil B cells |
| Isotype | IgG2a k |
| Notes | Recognizes a protein of 30-33kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type. |
| Alias Names | APY; ATOPY; B-lymphocyte cell-surface antigen B1; Bp35; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; Leukocyte surface antigen L |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (1-2ug/ml); Western Blotting (1-2ug/ml);,Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) |
| Shipping Information | Blue Ice |
| Size | 20 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | P11836 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
