Article No
36-3477-100
CD3e (T-Cell Marker)
Anti-CD3e (T-Cell Marker) Monoclonal Antibody(Clone: OKT3)
Antibodies Primary
Specifications
| Application | FA, FC, IF, IHC |
| Article No | 36-3477-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | OKT3 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD3e (T-Cell Marker) Monoclonal Antibody(Clone: OKT3) |
| Supplier | Abeomics |
| Entrez Gene ID | 916 |
| Gene Symbol | CD3E |
| Immunogen | Human PBMCs |
| Isotype | IgG2a k |
| Notes | Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. This MAb has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. |
| Alias Names | CD3 epsilon, CD3 TCR complex, CD3e antigen epsilon polypeptide (TiT3 complex), T cell antigen receptor complex epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (0.5-1ug/million cells); ,Immunohistochemistry (acetone fixed frozen sections); ,Immunofluorescence (1-2ug/ml); ,Functional Studies (Order Ab without Azide) |
| Shipping Information | Blue Ice |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of Ab Purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml. |
| UniProt Number | P07766 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
