Article No
36-3462-0.5
Application | FC, IF |
Article No | 36-3462-0.5 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | BH1 |
Clone Type | monoclonal |
Conjugation | CF488 |
Description | Anti-CD2 / Lymphocyte Function Antigen 2 (LFA-2) Monoclonal Antibody(Clone: BH1)-CF488 |
Supplier | Abeomics |
Entrez Gene ID | 914 |
Gene Symbol | CD2 |
Immunogen | Human CD2 protein |
Isotype | IgG2b k |
Notes | CD2 interacts throµgh its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells. |
Alias Names | Erythrocyte receptor; Ly-37; Lymphocyte function antigen 2 (LFA-2); LFA-3 receptor; Rosette receptor; SRBC; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11 |
Product Type | Antibodies Primary |
Protocol | Flow Cytometry: 5ul per test per one million cells (or 5ul per 100ul of whole blood); Immunofluorescence (1:50-1:100) |
Shipping Information | Blue Ice |
Size | 0.5 ml at µg/ml |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
Substrate / Buffer | Antibody Purified from Bioreactor Concentrate by Protein A/G and conjµgated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format. |
UniProt Number | P06729 |
Product Page Updated | 2024-02-06T07:35:53.072Z |