Article No
36-2945-100
Application | FC, IF, WB |
Article No | 36-2945-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 10B2 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Anti-Plakophilin-1 (PKP1) Monoclonal Antibody(Clone: 10B2) |
Supplier | Abeomics |
Entrez Gene ID | 5317 |
Gene Symbol | PKP1 |
Immunogen | N-terminus of human Plakophilin-1 protein |
Isotype | IgG1 k |
Notes | Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. |
Alias Names | B6P; Band 6 protein; PKP1; Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome) |
Product Type | Antibodies Primary |
Protocol | Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml) |
Shipping Information | Blue Ice |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human, mouse |
Storage | 4°C, -80°C |
Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
UniProt Number | Q13835 |
Product Page Updated | 2024-02-06T07:35:53.072Z |