Article No
36-2911-20
Application | IHC, WB |
Article No | 36-2911-20 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | rC31.3 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Anti-CD31 / PECAM-1 (Endothelial Cell Marker) Monoclonal Antibody(Clone: rC31.3) |
Supplier | Abeomics |
Entrez Gene ID | 5175 |
Gene Symbol | PECAM1 |
Immunogen | Recombinant full-length human CD31 protein |
Isotype | IgG1 k |
Notes | CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence. |
Alias Names | EndoCAM; PECA1; Platelet Endothelial Cell Adhesion Molecule 1; GPIIA' |
Product Type | Antibodies Primary |
Protocol | Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
Shipping Information | Blue Ice |
Size | 20 µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C, -80°C |
Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
UniProt Number | P16284 |
Product Page Updated | 2024-02-06T07:35:53.072Z |