Article No
36-2297-20
MART-1 / Melan-A / MLANA (Melanoma Marker)
Anti-MART-1 / Melan-A / MLANA (Melanoma Marker) Monoclonal Antibody(Clone: rMLANA/788)
Antibodies Primary
Specifications
| Application | IHC, WB |
| Article No | 36-2297-20 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | rMLANA/788 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-MART-1 / Melan-A / MLANA (Melanoma Marker) Monoclonal Antibody(Clone: rMLANA/788) |
| Supplier | Abeomics |
| Entrez Gene ID | 2315 |
| Gene Symbol | MLANA |
| Immunogen | Recombinant full-length hMART-1 protein |
| Isotype | IgG1 k |
| Notes | This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
| Alias Names | Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA |
| Product Type | Antibodies Primary |
| Protocol | Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Shipping Information | Blue Ice |
| Size | 20 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | 4°C, -80°C |
| Substrate / Buffer | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| UniProt Number | Q16655 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
