Article No
36-1956-100
CD63 (Late Endosomes Marker)
Monoclonal Antibody to CD63 (Late Endosomes Marker)(Clone : NKI/C3)
Antibodies Primary
Specifications
| Application | FC, IF, IHC |
| Article No | 36-1956-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | NKI/C3 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to CD63 (Late Endosomes Marker)(Clone : NKI/C3) |
| Supplier | Abeomics |
| Entrez Gene ID | 967 |
| Gene Symbol | CD63 |
| Immunogen | Smooth plasma membrane fraction of MeWo cells |
| Isotype | IgG1 k |
| Keywords | Antibodies, Cancer Marker, CD63 (Late Endosomes Marker), CD63, 967, P08962, CD63, MLA1, TSPAN30, NKI/C3, Smooth plasma membrane fraction of MeWo cells, Monoclonal Antibody to CD63 (Late Endosomes Marker)(Clone : NKI/C3), Antibody to CD63 (Late Endosomes Marker), Anti-CD63 (Late Endosomes Marker) Antibody, CD63 (Late Endosomes Marker) Antibody |
| Notes | This MAb recognizes protein of 26kDa-60kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression. |
| Alias Names | CD63||MLA1||TSPAN30 |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) |
| Purification | Affinity Purified |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P08962 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
