Article No
36-1678-100
gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)
Monoclonal Antibody to gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(Clone : HMB45)
Antibodies Primary
Specifications
| Application | FC, IF, IHC, WB |
| Article No | 36-1678-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | HMB45 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(Clone : HMB45) |
| Supplier | Abeomics |
| Entrez Gene ID | 6490 |
| Gene Symbol | PMEL |
| Immunogen | Extract of pigmented melanoma metastases from lymph nodes |
| Isotype | IgG1 k |
| Keywords | Antibodies, Cancer Marker, gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker), PMEL, 6490, P40967, PMEL, D12S53E, PMEL17, SILV, HMB45, Extract of pigmented melanoma metastases from lymph nodes, Monoclonal Antibody to gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker)(Clone : HMB45), Antibody to gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker), Anti-gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) Antibody, gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) Antibody |
| Notes | By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa). |
| Alias Names | PMEL||D12S53E||PMEL17||SILV |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Western Blot (2-4ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Purification | Affinity Purified |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P40967 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
