Article No
36-1048-100
Chromogranin A / CHGA (Neuroendocrine Marker)
Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : LK2H10)
Antibodies Primary
Specifications
| Application | IHC |
| Article No | 36-1048-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | LK2H10 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : LK2H10) |
| Supplier | Abeomics |
| Entrez Gene ID | 1113 |
| Gene Symbol | CHGA |
| Immunogen | Human pheochromocytoma |
| Isotype | IgG1 k |
| Keywords | Antibodies, Cancer Marker, Chromogranin A / CHGA (Neuroendocrine Marker), CHGA, 1113, P10645, CHGA, LK2H10, Human pheochromocytoma, Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : LK2H10), Antibody to Chromogranin A / CHGA (Neuroendocrine Marker), Anti-Chromogranin A / CHGA (Neuroendocrine Marker) Antibody, Chromogranin A / CHGA (Neuroendocrine Marker) Antibody |
| Notes | Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin. |
| Alias Names | CHGA |
| Product Type | Antibodies Primary |
| Protocol | Immunohistochemistry (Formalin-fixed) (0.1-0.2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) |
| Purification | Affinity Purified |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, rat |
| Storage | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
| Substrate / Buffer | 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| UniProt Number | P10645 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
