Article No
35-1553-100
4E-BP1
Polyclonal Antibody to 4E-BP1 (Ab-36)
Antibodies Primary
Specifications
| Application | IHC, WB |
| Article No | 35-1553-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Polyclonal Antibody to 4E-BP1 (Ab-36) |
| Supplier | Abeomics |
| Entrez Gene ID | 1978 |
| Gene Symbol | EIF4EBP1 |
| Immunogen | Peptide sequence around aa.34~38 (S-T-T-P-G) derived from Human 4E-BP1. |
| Isotype | IgG |
| Keywords | Antibodies, Cell Signalling, 4E-BP1 (Ab-36), EIF4EBP1, 1978, Q13541, EIF4EBP1, PHAS-1, Polyclonal Antibody to 4E-BP1 (Ab-36), 4E-BP1 (Ab-36) Polyclonal Antibody |
| Notes | 4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
| Alias Names | EIF4EBP1|| PHAS-1 |
| Product Type | Antibodies Primary |
| Protocol | Predicted MW: 18kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100 |
| Research area | Cell Signaling |
| Shipping Information | Blue Ice |
| Size | 100 µl |
| Source / Host | rabbit |
| Species Reactivity | human, mouse, rat |
| Storage | Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thaw cycle |
| Substrate / Buffer | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UniProt Number | Q13541 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
