Article No
318-61069
Additional Information | found in human and monkey |
Application | WB |
Article No | 318-61069 |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Clone | 303.9 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | anti-AAV Replicase, 303.9, mouse mab |
Supplier | Progen |
Immunogen | recombinant AAV2 Rep 78 protein, N-terminally truncated by 171 aa |
Isotype | IgG1 |
Notes | Mab 303.9 reacts with Rep proteins (Rep78, Rep68, Rep52 and Rep40) of human AAV2-infected cells, and also with serotypes 1,3,5, 6, 7, 8,9 and 10 (4, 11 and 12 negative) (Mietzsch et al. 2014). A weak cross-reactivity is seen in some human cell lines. Mietzsch, M. et al. OneBac: Platform for Scalable and High-Titer Production of Adeno-Associated Virus Serotype 1–12 Vectors for Gene Therapy. Hum. Gene Ther. 25, 212–222 (2014). |
Product Type | Antibodies Primary |
Purification | protein A affinity chromatography |
Size | 50 µg |
Source / Host | mouse |
Species Reactivity | virus |
Storage | short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles |
Substrate / Buffer | lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4) |
Technical Specifications | Recognizes AAV replicase proteins Rep 78, Rep 68, Rep 52 and Rep 40 in human AAV-2-infected cells. Cross-reactivity with AAV serotypes 1, 3, 5, 6, 7, 8,9 and 10 (4, 11 and 12 were negative). A weak cross-reactivity is seen in some human cell lines. |
Product Page Updated | 2024-01-25T14:16:46.985Z |