Article No
318-61057
AAV VP1/VP2
anti-AAV VP1/VP2, A69, mouse mab
Antibodies Primary
Specifications
| Additional Information | weak cross-reaction with serotypes 1, 3, and 6 |
| Application | IHC, IP, WB |
| Article No | 318-61057 |
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Clone | A69 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | anti-AAV VP1/VP2, A69, mouse mab |
| Supplier | Progen |
| Immunogen | adeno-associated virus 2 capsid proteins and virus particles |
| Isotype | IgG1 |
| Notes | A69 reacts with VP 1 and VP 2 of adeno-associated virus which are highly enriched in the nucleus. Epitope mapping experiments (Wobus et al. 2000) identified aa169 to aa184 of VP2 and (with reduced intensity) aa123 to aa136 of VP1 capsid proteins as the specific binding region. Wobus, C. E. et al. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 74, 9281–93 (2000). |
| Product Type | Antibodies Primary |
| Purification | protein A affinity chromatography |
| Size | 50 µg |
| Source / Host | mouse |
| Species Reactivity | virus |
| Storage | short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles |
| Substrate / Buffer | lyophilized; reconstitute in 1 ml dist. water (final solution contains 0.09 % sodium azide, 0.5% BSA in PBS buffer, pH 7.4) |
| Technical Specifications | Recognizes AAV-2 viral capsid proteins VP1 and VP2, which are highly enriched in the nucleus. Weak cross-reaction with serogroups 1, 3, and 6. |
| Product Page Updated | 2024-01-25T14:16:46.985Z |
