Article No
318-610160
Additional Information | published data: no cross-reaction with other AAV types in IF microscopy. With dot blot weak cross-reactivity with type 1, 3, 7 and 10. |
Application | WB, ELISA, IHC, IP, Neutralization |
Article No | 318-610160 |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Clone | ADK8 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | anti-AAV8, ADK8, mouse mab |
Supplier | Progen |
Immunogen | adeno-associated virus type 8 (AAV8) capsid proteins and virus particles |
Isotype | IgG2a k |
Notes | For characterization of different stages of infection and very useful for the analysis of the AAV assembly process. ADK8 specifically reacts with intact adeno-associated virus particles, empty and full capsids. Recognizes a conformational epitope of assembled capsids. Predicted binding site: residues 586-LQQQNT-591 (Gurda et al. 2012). The antibody cannot be used for immunoblotting using denaturing conditions. Gurda, B. L. et al. Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8. J. Virol. 86, 7739–7751 (2012). |
Product Type | Antibodies Primary |
Purification | protein A affinity chromatography |
Size | 50 µg |
Source / Host | mouse |
Species Reactivity | virus |
Storage | short term at 2 – 8 °C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles |
Substrate / Buffer | lyophilized; after reconstitution with 1 ml dist. water solution contains 0.09% sodium azide and 0.5% BSA in PBS |
Technical Specifications | For characterization of different stages of infection and very useful for analysis of the AAV assembly process. ADK8 specifically reacts with intact adeno-associated virus particles, empty and full capsids. Recognizes a conformational epitope of assembled capsids. Not for use in immunoblotting. |
Product Page Updated | 2024-01-25T14:16:46.985Z |