Article No
303-X1217C
Sphingosine 1 Phosphate Receptor 1 (EDG-1)
Sphingosine 1 Phosphate Receptor 1 (EDG-1)
Lysates
Specifications
| Application | WB |
| Article No | 303-X1217C |
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Concentration | See vial for concentration |
| Conjugation | Unconjugated |
| Description | Sphingosine 1 Phosphate Receptor 1 (EDG-1) |
| Supplier | Exalpha Biologicals |
| Notes | EDG-1 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-1 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-1 is expressed in cardiovascular, leukocyte- containing and other tissues. |
| Alias Names | EDG1 (S1P1) Transfected Cell Positive Control Lysate |
| Product Type | Lysates |
| Protocol | For use as a positive control with Exalpha's EDG1 (S1P1) polyclonal antibody (Cat. No. X1093P) for Western blot analysis. |
| Shipping Information | Ship at ambient temperature, freeze upon arrival |
| Size | 100 µl |
| Stability | See expiration date on vial |
| Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
| Substrate / Buffer | Provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol |
| Technical Specifications | For use as a positive control with Exalpha's EDG1 (S1P1) polyclonal antibody (Cat. No. X1093P) for Western blot analysis. |
| Product Page Updated | 2023-12-29T14:25:47.027Z |
