Article No
303-N105P
Sheep anti Human Rhombotin 2
Sheep anti Human Rhombotin 2
Antibodies Primary
Specifications
| Article No | 303-N105P |
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | See vial for concentration |
| Conjugation | Unconjugated |
| Description | Sheep anti Human Rhombotin 2 |
| Supplier | Exalpha Biologicals |
| Immunogen | Full length rhombotin 2 protein |
| Isotype | IgG |
| Notes | Two homologues of the rhombotin gene have now been isolated. One of these, designated Rhom-2, is located on human chromosome 11 at band 11p13, where a cluster of T-cell leukemia-specific translocations occur; all translocation breakpoints at 11p13 are upstream of the Rhom-2 gene. Human and mouse Rhom-2 are highly conserved and, like rhombotin, encode two tandem cysteine-rich LIM domains. Rhom-2 mRNA is expressed in early mouse development in central nervous system, lung, kidney, liver, and spleen but only very low levels occur in thymus. The Rhom-2 gene is such a common site of chromosomal damage in T-cell tumors. Chromosome bands 11p15 (rhombotin) and 11p13 (Rhom-2) are consistent sites of chromosome translocation in T-cell leukemia, with the 11p15 target more rarely involved. |
| Alias Names | LIM domain only protein; cysteine-rich protein TTG-2; T-cell translocation protein 2 |
| Product Type | Antibodies Primary |
| Protocol | Western Blots at 1-10 ug /ml |
| Purification | Ammonium Sulfate Precipitation |
| Research area | Inflammation |
| Shipping Information | Room Temperature |
| Size | 250 µg |
| Source / Host | sheep/ovine |
| Species Reactivity | human |
| Stability | See expiration date on vial |
| Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
| Substrate / Buffer | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| Technical Specifications | Western Blots at 1-10 ug /ml |
| UniProt Number | P25791 (Human) |
| Product Page Updated | 2023-12-29T14:25:47.027Z |
