Article No
303-CO20141-0.1
Article No | 303-CO20141-0.1 |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Concentration | app. 1 mg/ml |
Control Tissue | Rat skin |
Description | Collagen Type I, rat |
Supplier | Exalpha Biologicals |
Immunogen | Purified collagen type I from rat skin |
Notes | Type I Collagen usually exists as a heterotrimer formed by alpha 1(I) and alpha 2(I) chains and is found in bone, cornea, skin and tendon. In foetal tissues also homotrimers of alpha-1(I) are found, but they are not constituents of normal adult tissues. Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Rat collagen type I 100%, rat collagen II, III, IV and V <0.1%; rat elastin and fibronectin <0.1% ( RIA at 1:200 dilution). |
Product Type | Antibodies Primary |
Protocol | IHC(P), IFA, ELISA, RIA, IB/WB |
Purification | affinity purified antibody lyophilized from phosphate buffered solution; no BSA and preservative added! |
Size | 0.1 ml |
Source / Host | rabbit |
Storage | -20°C |
Substrate / Buffer | Delipidated, heat inactivated lyophilized stable whole serum. No preservative added, as it may interfere with the antibody activity. No foreign protein added. Total protein and IgG concentration in the antiserum are comparable to those of pooled donkey serum. No foreign proteins added. It is reconstituted by adding 1 ml sterile distilled water. |
Technical Specifications | IHC(P), IFA, ELISA, RIA, IB/WB |
UniProt Number | P02454 |
Product Page Updated | 2023-12-29T14:25:47.027Z |