Article No
30-2402-100
CD169 / Siglec-1
Anti-CD169 / Siglec-1 Monoclonal Antibody (Clone:7-239)-PE Conjugated
Antibodies Primary
Specifications
| Application | FA, FC, IHC, IP, WB |
| Article No | 30-2402-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 7-239 |
| Clone Type | monoclonal |
| Conjugation | PE |
| Description | Anti-CD169 / Siglec-1 Monoclonal Antibody (Clone:7-239)-PE Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 6614 |
| Gene Symbol | SIGLEC1 |
| Immunogen | human rhinovirus 14-infected monocyte-derived dendritic cells |
| Isotype | IgG1 |
| Notes | CD169, also known as Siglec-1 or sialoadhesin, is a type I transmembrane glycoprotein of the sialic acid binding Ig-like lectin family. It binds to sialylated glycoproteins on various haematopoietic cells to mediate cell-cell interactions. CD169 is expressed on a subset of macrophages and dendritic cells. On CD14+ monocytes its expression can be induced by interferon alpha and gamma. High expression of CD169 is observed in the spleen, lymph nodes, bone marrow, and under inflammatory conditions rheumatoid arthritis and atherosclerosis, lower in the liver, lungs and gut. It has been shown to be involved in antigen presentation to invariant NKT cells, which play an important role in the innate arm of the immune system to modulate the subsequent acquired immune responses. |
| Alias Names | SIGLEC1||SN |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 100 Tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | Q9BZZ2 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
