Article No
30-2005-100
Application | FC, ICC, IHC, WB |
Article No | 30-2005-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 1H4 |
Clone Type | monoclonal |
Conjugation | FITC |
Description | Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:1H4)-FITC Conjugated |
Supplier | Abeomics |
Entrez Gene ID | 3383 |
Gene Symbol | ICAM1 |
Immunogen | Raji cells and spleen cells fused with NS1 cells |
Isotype | IgG2b |
Notes | CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
Alias Names | ICAM1 |
Product Type | Antibodies Primary |
Shipping Information | Blue Ice |
Size | 100 Tests |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
UniProt Number | P05362 |
Product Page Updated | 2024-02-06T07:35:53.072Z |