Article No
30-1936-100
CD7
Anti-CD7 Monoclonal Antibody (Clone:MEM-186)-FITC Conjugated
Antibodies Primary
Specifications
| Application | FC, IHC, IP, WB |
| Article No | 30-1936-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MEM-186 |
| Clone Type | monoclonal |
| Conjugation | FITC |
| Description | Anti-CD7 Monoclonal Antibody (Clone:MEM-186)-FITC Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 924 |
| Gene Symbol | CD7 |
| Immunogen | Human acute myelogenous leukaemia cell line KG-1. |
| Isotype | IgG1 |
| Notes | CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics. |
| Alias Names | CD7 |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 100 Tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P09564 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
