Article No
30-1906-0.1
CD19
Anti-CD19 Monoclonal Antibody (Clone:4G7 )-Biotin Conjugated
Antibodies Primary
Specifications
| Application | FC |
| Article No | 30-1906-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 4G7 |
| Clone Type | monoclonal |
| Conjugation | Biotin |
| Description | Anti-CD19 Monoclonal Antibody (Clone:4G7 )-Biotin Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 930 |
| Gene Symbol | CD19 |
| Immunogen | Human CCL (chronic lymphocytic leukemia) cells |
| Isotype | IgG1 |
| Notes | Specificity: The mouse monoclonal antibody 4G7 recognizes an extracellular epitope of human CD19. CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity. |
| Alias Names | CD19 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytrometry: Recommended dilution: 1 µg/ml. |
| Purification | Size-exclusion Chromatography |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P15391 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
