Article No
30-1896-0.1
CD117 / c-Kit
Biotin Conjugated, Anti-CD117 / c-Kit Monoclonal Antibody (Clone:104D2)
Antibodies Primary
Specifications
| Application | FC |
| Article No | 30-1896-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 104D2 |
| Clone Type | monoclonal |
| Conjugation | Biotin |
| Description | Biotin Conjugated, Anti-CD117 / c-Kit Monoclonal Antibody (Clone:104D2) |
| Supplier | Abeomics |
| Entrez Gene ID | 3815 |
| Gene Symbol | KIT |
| Immunogen | MOLM-1 megakaryocytic cells |
| Isotype | IgG1 |
| Notes | CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells. |
| Alias Names | KIT||SCFR |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P10721 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
