Article No
30-1896-0.1
Application | FC |
Article No | 30-1896-0.1 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 104D2 |
Clone Type | monoclonal |
Conjugation | Biotin |
Description | Biotin Conjugated, Anti-CD117 / c-Kit Monoclonal Antibody (Clone:104D2) |
Supplier | Abeomics |
Entrez Gene ID | 3815 |
Gene Symbol | KIT |
Immunogen | MOLM-1 megakaryocytic cells |
Isotype | IgG1 |
Notes | CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells. |
Alias Names | KIT||SCFR |
Product Type | Antibodies Primary |
Shipping Information | Blue Ice |
Size | 0.1 mg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
UniProt Number | P10721 |
Product Page Updated | 2024-02-06T07:35:53.072Z |