Article No
30-1744-100
Application | FA, FC, IHC, IP, WB |
Article No | 30-1744-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | BU63 |
Clone Type | monoclonal |
Conjugation | APC |
Description | Anti-CD86 Monoclonal Antibody (Clone:BU63)-APC Conjugated |
Supplier | Abeomics |
Entrez Gene ID | 942 |
Gene Symbol | CD86 |
Immunogen | B-lymphoblastoid cell line ARH 77 |
Isotype | IgG1 |
Notes | CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response. |
Alias Names | CD86||CD28LG2 |
Product Type | Antibodies Primary |
Shipping Information | Blue Ice |
Size | 100 Tests |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
UniProt Number | P42081 |
Product Page Updated | 2024-02-06T07:35:53.072Z |