Article No
30-1737-100
Application | FC, IHC |
Article No | 30-1737-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | SN3 |
Clone Type | monoclonal |
Conjugation | APC |
Description | Anti-CD24 Monoclonal Antibody (Clone:SN3)-APC Conjugated |
Supplier | Abeomics |
Entrez Gene ID | 100133941 |
Gene Symbol | CD24 |
Immunogen | Glycoproteins purified from human NALM-1 cell line. |
Isotype | IgG1 |
Notes | CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid. |
Alias Names | CD24||CD24A |
Product Type | Antibodies Primary |
Shipping Information | Blue Ice |
Size | 100 Tests |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
UniProt Number | P25063 |
Product Page Updated | 2024-02-06T07:35:53.072Z |