Article No
30-1727-0.1
CD261 / TRAIL-R1 / DR4
Anti-CD261 / TRAIL-R1 / DR4 Monoclonal Antibody (Clone:DR-4-02)-APC Conjugated
Antibodies Primary
Specifications
| Application | FA, FC, ICC, IP |
| Article No | 30-1727-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | DR-4-02 |
| Clone Type | monoclonal |
| Conjugation | APC |
| Description | Anti-CD261 / TRAIL-R1 / DR4 Monoclonal Antibody (Clone:DR-4-02)-APC Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 8797 |
| Gene Symbol | TNFRSF10A |
| Immunogen | Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1. |
| Isotype | IgG1 |
| Notes | TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor). |
| Alias Names | TNFRSF10A||APO2||DR4||TRAILR1 |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | O00220 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
