Article No
30-1718-100
CD63
Anti-CD63 Monoclonal Antibody (Clone:MEM-259)-APC Conjugated
Antibodies Primary
Specifications
| Application | FC, ICC, IHC, IP |
| Article No | 30-1718-100 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MEM-259 |
| Clone Type | monoclonal |
| Conjugation | APC |
| Description | Anti-CD63 Monoclonal Antibody (Clone:MEM-259)-APC Conjugated |
| Supplier | Abeomics |
| Entrez Gene ID | 967 |
| Gene Symbol | CD63 |
| Immunogen | HPB-ALL T cell line |
| Isotype | IgG1 |
| Notes | CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. It is also present in the plasma membrane, usually following cell activation. Hence, it has become an widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. |
| Alias Names | CD63||MLA1||TSPAN30 |
| Product Type | Antibodies Primary |
| Shipping Information | Blue Ice |
| Size | 100 Tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P08962 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
